Recent Publications

Primary Research Papers

Hamill, K.J., Hiroyasu, S., Colburn, Z.T., Ventrella, R.V., Hopkinson, S.B., Skalli, O. and Jones, J.C.R. (2015). Alpha actinin-1 regulates cell-matrix adhesion organization in keratinocytes: consequences for skin cell motility. J. Invest. Derm. 135: 1043-1052.

Morales-Nebreda, L.I., Rogel, M.R., Eisenberg, J.L., Hamill, K.J., Soberanes, S., Nigdelioglu, R., Takugo, M.C., Radigan, K.A., Ridge, K.M., Misharin, A.V., Woychek, A., Hopkinson, S., Perlman, H, Mutlu, G.M., Pardo, A., Selman, M., *Jones, J.C.R., *Budinger, G.R.S. (2015). Lung specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis. Am. J. Resp. Cell Mol. Biol. 52: 503-512. *Co-senior, contributing authors.

Kligys, K., Wu, Y., Hamill, K., Hopkinson, S., Budinger, G.R.S and Jones, J.C.R. (2013). Laminin-332 and α3β1 integrin-supported migration of bronchial epithelial cells is modulated by fibronectin. Am. J. Resp. Cell Mol. Biol. 49: 731-740.

Jeffe, J.S., Seshadri, S., Hamill, K.J., Huang, J.H., Carter, R., Suh, L., Hulse, K.E., Norton, J., Conley, D.B., Chandra, R.K., Kern, R.C., Jones, J.C.R., Schleimer, R.P. and Tan, B.K.. (2013). A role for anti-BP180 autoantibodies in chronic rhinosinusitis. LARYNGOSCOPE 123: 2104–2111.

Eisenberg, J.E., Beaumont, K.G., Takawira, D., Hopkinson, S.B., Mrksich, M., Budinger, G.R.S. and Jones, J.C.R. (2013) Plectin-containing, centrally-localized focal adhesions exert traction forces in primary lung epithelial cells. J. Cell Sci. 126: 3746-3755.

Hiroyasu, S., Ozawa, T., Kobayashi, H., Ishii, M., Aoyama, Y., Kitajima, Y., Hashimoto, T., Jones, J.C.R. and Tsuruta, D. (2013) Bullous pemphigoid IgG induces BP180 internalization via a macropinocytic pathway. Am. J. Pathol. 182: 828-840.

Hamill, K.J., Hopkinson, S.B., Skalli, O. and Jones, J.C.R. (2013) Actinin-4 in keratinocytes regulates motility via an impact on lamellipodia stability and matrix adhesions. FASEB J. 27: 546-556.

Kligys, K.R., Wu, Y., Hopkinson, S.B., Kaur, S., Platanias, L.C. and Jones, J.C.R. (2012). α6β4 integrin: a master regulator of the expression of integrins in human keratinocytes. J Biol. Chem. 287: 17975-17984.

Hamill, K.J., Hopkinson, S.B., Hoover, P., Todorović, V., Green, K.J. and Jones, J.C.R. (2012). Fibronectin expression determines skin cell motile behavior. J. Invest. Derm. 132: 448-457.

Fuerst, F.C., Gruber, G., Stradner, M.H., Jones, J.C., Kremser, M.L., Angerer, H., Setznagl, D., Glehr, M., Windhager, R., Leithner, A. and Graninger, W.B. (2011). Regulation of MMP3 by laminin alpha 4 in human osteoarthritic cartilage. Scand. J. Rheumatol. 40: 494-496.

Urich, D., Eisenberg, J.L., Hamill, K.J., Takawira, D., Chiarella, S.E., Soberanes, S., Gonzalez, A., Koentgen, F., Manghi, T., Hopkinson, S.B., Misharin, A., Perlman, H., Mutlu, G.M., Budinger, G.R.S. and Jones, J.C.R. (2011). Lung specific loss of laminin α3 confers resistance to mechanical injury. J. Cell Sci. 124: 2927-2937.

Hamill, K.J., Hopkinson, S.B., Jonkman, M. and Jones, J.C.R. (2011). Type XVII collagen regulates lamellipod stability, cell motility and signaling to Rac1 by targeting BPAG1e to α6β4 integrin. J. Biol. Chem. 286: 26768-26780.

Zhou, Q., Pardo, A., Königshoff, M., Eickelberg, O., Budinger, G.R., Thavarajah, K., Gottardi, C.J., Jones, J., Varga, J., Selman, M., Sznajder, J.I., Raj, J.U., and Zhou, G. (2011) Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis. FASEB J. 9: 33032–3044.

Takawira, D., Budinger G.R.S., Hopkinson, S.B. and Jones, J.C.R. (2011). A dystroglycan/plectin scaffold mediates mechanical pathway bifurcation in lung epithelial cells. J Biol. Chem. 286: 6301-6310.

Eisenberg, J.L., Safi, A., Wei, X., Espinosa, H.D., Budinger, G.R.S. and Jones, J.C.R. (2011). Substrate stiffness regulates extracellular matrix deposition by alveolar epithelial cells. Res. Rep. Biol. 2: 1-12.

Hayashida, T., Jones, J.C.R., Lee, C.K. and Schnaper, H.W. (2010). Loss of β1 integrin enhances TGF-β1-induced collagen expression in epithelial cells via increased αvβ1 integrin and Rac1 activity. J. Biol. Chem. 285: 30741-30751.

Todorovic, V., Desai, B.V., Schroeder Patterson, M.J., Amargo, E.V., Dubash, A.D., Yin, T., Jones, J.C.R. and Green, K.J. (2010). Plakoglobin regulates cell motility through Rho and fibronectin-dependent Src signaling. J. Cell Sci., 123: 3576-3586.

Karlsson, A.B., Maizels, E.T., Flynn, M.P., Jones, J.C., Shelden, E.A., Bamburg, J.R. and Hunzicker-Dunn, M. (2010). Luteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin. Mol. Endo., 24: 1765-81.

Ozawa, T., Tsuruta, D., Jones, J.C.R., Ishii, M., Ikeda, K., Harada, T., Kawada, A., and Kobayash, H. (2010). Dynamic relationship of focal contacts and hemidesmosome protein complexes in live cells. J. Invest. Derm. 130: 1624–1635.

Imanishi, H., Tsuruta, D., Tateishi, C., Sugawara, K., Paus, R., Tsuji, T., Ishii, M., Ikeda, K., Kunimoto, H., Nakajima., K, Jones, J.C. and Kobayashi H. (2010). Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia. J Dermatol Sci., 58: 43-54.

Refereed Reviews, Commentaries, Editorials and Short Papers

Hiroyasu, S. and Jones, J.C.R. (2014). A new component of the Fraser Complex. J Invest Dermatol. 134: 1192-1193.

Hopkinson, S.B., Hamill, K.J., Wu, Y., Hiroyasu, S. and Jones, J.C.R. (2014). Focal contact and hemidesmosomal proteins in keratinocyte migration and wound repair. Ad. Wound Care. 3: 247-263.

Tschumperlin, D., Jones, J. and Senior, R. (2012). The Fibrotic Matrix in Control: Does the Extracellular Matrix Drive Progression of Idiopathic Pulmonary Fibrosis? Am. J. Resp. Crit. Care Med. 186: 814-816.

Tsuruta, D., Hashimoto, T., Hamill, K.J. and Jones, J.C.R. (2011). Hemidesmosomes and focal contact proteins: Functions and cross-talk in keratinocytes, bullous diseases and wound healing. J. Dermatol. Sci. 62: 1-7.

Gonzalez, A.M., Bhattacharya, R., deHart, G.W. and Jones, J.C.R. (2010). Transdominant regulation of integrin function: Mechanisms of crosstalk. Cellular Signalling. 22: 578-583.

Non-Refereed Reviews, Commentaries and Research Papers

Jones, J.C.R. Single and double immunogold labeling of cells in culture and tissue specimens. Methods in Molecular Biology. Eds. Skalli, O and Schwartzbach, S. In press.

Hamill, K.J., Paller, A.S. and Jones, J.C.R. (2010). Adhesion and migration, the diverse functions of the laminin α3 subunit. Dermatol. Clin. 28: 79 -87.